In this episode, host Scott Larrivee speaks with Dr. Luke Nordquist, a medical oncologist and Founder/CEO of XCancer, a globally recognized clinical research center. Dr. Nordquist shares the origin story of XCancer—born out of a desire to bring cutting-edge prostate cancer trials to community care settings—and how it has grown into a nationwide clinical research network supporting over 45 community cancer centers. With a patient-first philosophy, Luke discusses building operational efficiency, launching world-first trials, and developing proprietary research software to streamline clinical operations.
They dive deep into the challenges and myths surrounding clinical trial participation. Dr. Nordquist debunks misconceptions around cost, access, and patient eligibility while underscoring the life-extending value trials offer. He explains how only 3–5% of cancer patients enroll in trials, often due to a lack of awareness, and why reshaping this narrative is essential. His approach includes integrating trial options into routine care and building relationships with pharmaceutical sponsors, helping bring innovative treatments to patients in both urban and rural settings.
Scott and Luke also explore the future of theranostics, including X Cancer’s expansion into radiopharmaceutical clinical trials. Dr. Nordquist introduces TheranosticTrials.org, a first-of-its-kind patient- and provider-friendly platform that consolidates trials, education, and industry resources into one hub. The episode closes with a visionary look at democratizing access to cancer innovation globally, including in Tanzania—and even features a detour into Dr. Nordquist’s X Cancer Motorsports team, led by his son on the road to Indy.
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Time Stamps:
*(01:28) How XCancer came to Existence
*(03:58) Expanding Research and Collaborations
*(08:44) Expanding Clinical Trials and Patient Perspectives
*(21:11) Overcoming the Challenges in Clinical Research
*(24:10) Theranostic Trials and Community Centers
*(31:46)What is the Future of Theranostics and Global Expansion
*(34:48) XCancer’s Own Branded Race Car
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‘Talk Radioisotopes: Going Nuclear on Cancer’ is brought to you by Nusano, a physics company whose breakthrough technologies are poised to help supply the fight against cancer and enable innovation across multiple industries. Find out more at Nusano.com.
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Links:
Visit XCancer
Talkradioisotopes.com
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